When I ordered my UV-5R, I didn't order a programming lead. As I have commented before, I recommend you do! Manual programming is rather arcane, especially for repeater/duplex frequencies.
I'd used a Wouxun lead that I'd borrowed to get the first few memories set up. Yesterday, the lead I had ordered from Hong Kong arrived. Installation of the driver didn't go quite as smoothly as I'd hoped! I tried running the executable but had no luck. In the end I followed some instructions I found to install the driver manually and it worked. The PC I was working on runs Vista. Perhaps that's why it was awkward.